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Since berberine may not be suitable for everyone and can interact with certain medicines, it is important to consult a doctor before starting

A popular dual agonist, tirzepatide (Mounjaro), activates both GLP-1R and GIPR, producing synergistic effects on insulin secretion, appetite suppression, and weight reduction (Table 1)

How do GLP-1 supplements work

The prevalence of clinically significant PBH varies considerably, with estimates ranging from 0.2% to 34% depending on diagnostic criteria (symptomatic reporting versus continuous glucose monitoring) and surgical procedure (more common after RYGB than sleeve gastrectomy)

The first 4 to 8 weeks are the adjustment window

Although final treatment guidelines will depend on future approvals, obesity specialists believe certain patient groups may benefit the most