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"More frequent monitoring might be appropriate if you're losing weight rapidly, eating very little, experiencing significant fatigue, hair loss or treating a known deficiency," says Pratt

Retatrutide has a half-life of approximately 6 days, which supports once-weekly dosing and reaches steady state within 4-5 weeks at each dose level

Long-term supplementation provides additional benefits for insulin resistance and pancreatic function, especially in people with vitamin D deficiency

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"As we've gotten more approvals for weight management, it's been fantastic