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These two pathways cooperate in several ways: IFN-I generated by cGAS-STING heightens NLRP3 sensitivity, and NLRP3-dependent IL-1 upregulates cGAS via NF-KB, creating a positive-feedback loop

Meet the experts Shereene Idriss, MD, a board-certified dermatologist and founder of Idriss Dermatology in New York City

Studies on ascorbic acid derivatives suggest they may suppress inflammatory mediators that exacerbate PIH development in darker skin tones

In studies with rodents, Ozempic and medicines that work like Ozempic caused thyroid tumors, including thyroid cancer

If you are new to it, some combinations can overwhelm the skin if used incorrectly

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