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And small peptide GLP-1 analogues have been demonstrated to cross BBB via peripheral administration, including LG, lixisenatide and exendin-4 (72)

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Long-term treatment with acetyl-L-carnitine (1.5-3g daily for 3+ months) was safe and significantly improved the patients mental condition [12]

17 PPAR is mostly expressed in the adipose tissue and controls lipogenesis, adipocyte differentiation, and glucose metabolism

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