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Moreover, Vitamin C has also been found to promote the production of vascular NO, the importance of which weve discussed earlier in the article

The overall impression from available evidence is that DSIP appears reasonably well-tolerated with a low incidence of serious adverse effects in the populations and contexts studied, but significant gaps in safety knowledge remain, particularly regarding long-term use, use in specific populations (elderly, children, those with comorbidities), and comprehensive toxicology assessment meeting modern pharmaceutical standards

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Both forms are designed to improve delivery, but they have not been adequately compared against each other in robust human trials