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These compounds are also therapeutic agents in the treatment of oxidative stress-related diseases
In comparison to Ex-4, PEx-4 was more efficient in improving BACCO-induced cognitive impairment and cortical edema in diabetic rats (96)
Mice lacking sodium channel beta1 subunits display defects in neuronal excitability, sodium channel expression, and nodal architecture
miR-122 promotes hepatic lipogenesis via inhibiting the LKB1/AMPK pathway by targeting Sirt1 in non-alcoholic fatty liver disease
These findings underscore the potential for peptide sequence optimization to fine-tune receptor selectivity or balanced activation, providing tailored approaches for treating different diseases 14