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In some instances, localized administration in the ear allows an active agent to reach a target organ (e.g., inner ear) in the absence of systemic accumulation of the active agent

Bhardwaj, S., Jindal, A., Singh, S., Kaur, R

Redox Chemistry of CopperAmyloid: The Generation of Hydroxyl Radical in the Presence of Ascorbate is Linked to RedoxPotentials and Aggregation State Luc Guilloreau, Sarah Combalbert, Alix SourniaSaquet, et al

No published human trial has measured outcomes for the 3-peptide combination together

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Alharbe R, Almansour A, Kwon DH