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Exendin-4 (a peptide that shares 53% amino acid sequence with native GLP-1), however, was found to be effective in rat models for preventing 6-OHDA-induced DA-ergic neuron loss and increasing the number of neural stem cells in the subventricular zone (Erbil et al., 2019)

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However, a cavity on the capsid surface at an inter-protomer interface, where we previously reported extra electron density 7 , has recently been identified as potentially druggable, with micro-molar binding for a benzene-sulfonamide derivative 8

doi:10.1016/j.yrtph.2020.104665 Chang CH, Tsai WC, Lin MS, Hsu YH, Pang JHS

Tumor necrosis factor-induced nonapoptotic cell death requires receptor-interacting protein-mediated cellular reactive oxygen species accumulation