In these models, Cre recombinase is fused to a mutated estrogen receptor (ER T2 ) which retains Cre in the cytoplasm until the receptor binds its ligand, the selective estrogen receptor modulator TAM (Feil et al., 1997
Although treatments are usually effective for managing thyroid function, individual genetic, environmental, or lifestyle factors that affect disease outcome and/or response to therapy are generally ignored
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Chen X, Maniotis A, Majumdar D, et al
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