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The tidal volume was adjusted for each animal to provide normal chest expansion

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In this respect, it should also be noted that the influence of PO was generally stronger in erythrocytes, with analog plasmatic metabolites showing similar levels regardless of PO status (e.g., carbohydrate-related metabolites, branched-chain amino acids, oxidative stress byproducts, nucleotide catabolites)

Individual variation in drug response is significantbiological differences in GLP-1 receptor expression and function may contribute to why some patients naturally respond more robustly than others, though this is not routinely assessed in clinical practice