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The luciferase signal in the presence of GnHCl, measures the level of translation of the transfected replicon, which in BSO treated and untreated cells, was at normal levels

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BMI = 22 (2) kg/m 2 ] received either 90 days of Protandim [1 pill a day, n = 19)] or placebo (n = 19)

This dosage is increased by 2.5mg every four weeks until a maximum of 15mg/weekly is reached [23]