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The challenges and potential risks faced by GLP-1RAs in clinical practice With the rapid expansion of the clinical application scope of GLP-1RAs, especially among the elderly and those at risk of sarcopenia, its potential limitations and risks are receiving increasing attention

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If this process is inefficient, it can lead to a condition known as non-alcoholic fatty liver disease (NAFLD), or worsen a pre-existing case

Sinomenine (SIN) can alleviate the symptoms of CIA by targeting Lactobacillus and microbial tryptophan metabolites to activate the aryl hydrocarbon receptor (AhR) and modulate the Th17/Treg balance (Jiang et al., 2023