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The dose starts small and is gradually increased each week

It also plays a vital role in red blood cell production and oxygen delivery to tissues

Histamine intolerance results from impaired histamine breakdown by diamine oxidase (DAO), causing symptoms such as headaches, flushing, and gastrointestinal disturbances

Consequently, dose titration is slow and dependent on AEs, and common recommendations like reduction on food quantity or high fat or spicy food is always suggested (151, 154, 158) Also, some hypotheses might suggest that GLP-1 stimulation can affect taste perception, as it has been reported by the FDA Adverse Event Reporting System (FAERS)

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