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The phase 3 SURMOUNT programme assessed the safety and efficacy of tirzepatide as obesity treatment and the medication has now been approved (November 2023) for chronic weight management by the US Food and Drug Administration (FDA) and the European Medicines Agency (EMA) [46, 47]

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Back Eng, J (1993) 'Exendin-3 and exendin-4 polypeptides, and pharmaceutical compositions comprising same', US Patent 5,424,286

Healthy habits like eating better and exercising more can reduce the risk of significant weight regain

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