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Following the development of motor symptoms, cognitive dysfunctions progress due to the involvement of the atemporal cortex (Kalia 2018)

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Dulaglutide's Metabolic Fate Dulaglutide is a large peptide (GLP-1 analog fused to an IgG4 Fc fragment)

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The core of our discussion presents a deep dive into an expanded mechanistic tapestry, where we integrate classical pathways with cutting-edge discoveries in epigenetics (e.g., protein arginine methyltransferase 5 (PRMT5) inhibition), cell death (ferroptosis), and immunomodulation

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