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Future studies should explore the optimal stimulation parameters for tVNS targeting different PD symptoms on the basis of proving the efficacy of tVNS, in order to provide more precise and efficient treatment options for PD patients

Originally identified during investigations involving sleep physiology and neurological regulation, DSIP peptide has attracted substantial scientific interest due to its unique structure and potential interactions with biological systems associated with sleep cycles and neuroendocrine signaling

determined by an assay that is specific, sensitive, reproducible and robust