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Therapeutic Advances in Chronic Disease, 13
Conclusion: This NMA shows heterogeneous effects of nutraceuticals on obesity-related outcomes
Wegovy (semaglutide) is a GLP-1 medication that helps with weight loss by reducing appetite, increasing fullness, and lowering food noise. Until recently, Wegovy was best known as a weekly injection
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Recent investigations from 2023 to 2025 highlight several key findings: microneedle-based delivery consistently reduced neuropathic pain [94], improved nerve function through precise local drug application [95], promoted regeneration when combined with stem cellderived products or electrically responsive systems [96], and decreased inflammation when loaded with anti-inflammatory agents [97]
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