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Authored by: Karla K

Participants who started too high or escalated too quickly in clinical trials experienced nearly double the rate of nausea and vomiting compared to those who followed the gradual protocol

Phase 2 results (48 weeks, published in NEJM) The landmark Phase 2 trial randomized 338 participants across multiple dose groups

All prescribing decisions, including custom dosing and titration protocols, must be made by a licensed clinician based on individual patient clinical need

Proteomic changes upon treatment with semaglutide in individuals with obesity

Two patients can choose the same medication but need very different dose strategies