POTS is also directly related to Hcy levels, at least in the young (Li et al., 2018)
(PubMed) Pal J, Sanal MG, Gopal GJ
It consists of 463 amino acids ( Figure 2 ) for a more detailed figure, refer to reference 18
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Pigmentation can affect any part of the body and can be of different types, such as tanning, melasma, post-inflammatory hyperpigmentation (PIH), acanthosis nigricans, freckles, liver spots, age spots, generalized pigmentation, drug-induced pigmentation, birthmarks, and under-eye dark circles
Clinical indications include deficiency due to inadequate diet or malabsorption, drug-induced deficiency (for example, from long-term isoniazid or oral contraceptives), and certain inborn errors of metabolism (such as pyridoxine-dependent seizures or sideroblastic anemia)