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By purchasing this product, the buyer acknowledges and agrees that it is sold strictly for research and laboratory purposes only and understands the limitations of its intended use

COMT normally converts: Levodopa 3-O-methyldopa (3-OMD) Dopamine metabolism also increases Tolcapone blocks COMT Increases levodopa levels in blood Increases levodopa delivery to brain Prolongs levodopa duration of action Reduces wearing-off symptoms Reduces motor fluctuations Special Point: Tolcapone inhibits COMT both in peripheral tissues and in the CNS, unlike entacapone (mostly peripheral)

Once a patient hits their ideal weight, they can continue on maintenance treatments or decide to go off treatment

There are two major sub-classes of peroxiredoxins, 1-cys Prdx (commonly known as Prdx VI) and 2-cys Prdx

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PMID 16377242