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Higher scores indicated more severe degeneration [1]

How AOD-9604 Works AOD-9604 is a modified fragment of human growth hormone derived from amino acids 176-191 of the HGH molecule

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Inhibition of lipid synthase activity: AOD 9604 reduces the activities of fatty acid synthase (FAS) and acetyl-CoA carboxylase (ACC), and decreases de novo synthesis of fatty acids

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Researchers also observed shifts in glucose uptake and sirtuin activity (the SIRT1 longevity protein family) when NNMT was blocked