Directly, the copper coordination prevents free copper-catalyzed Fenton reactions that generate hydroxyl radicals, while the peptide sequence itself can scavenge existing reactive oxygen species
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Ideally, this framework is further enriched with metagenomic analysis of the gut microbiome, which provides valuable insights for functional decision-making (Proctor et al., 2019), and with a pharmacogenomic profile, particularly in cases requiring pharmacotherapy or where patients are already on complex polypharmacy regimens
Reference: Wu G et al
At standard doses of 1 to 2 mg per day for a 70 kg person, the copper load is approximately 300-fold below the toxic threshold (Pickart & Margolina, 2018)
Kim MH, Kim H (2017) The roles of glutamine in the ntestine and ts mplication in ntestinal diseases