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The 52-week safety extension trial (Falutz et al., PMID 20101189) extended these observations and reported no new safety signals

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The MMP paradox Matrix metalloproteinases, or MMPs, are enzymes that break down collagen and other structural proteins in the skin

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While it naturally occurs in the body and helps to defend skin against the visible effects of environmental damage, like all good things, supplies dwindle as we age

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The magic happens at the cellular level

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doi:10.1101/gad.478408

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