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This ratio was vehicle-corrected by subtracting the response of vehicle-treated wells from the ratio of ligand-treated wells and then baseline-corrected by subtracting to the mean BRET ratio of baseline values (prestimulation) for each well

doi: 10.1016/j.molmet.2025.102124

Drugs such as semaglutide (Ozempic and Wegovy, both Novo Nordisk), as well as tirzepatide (Mounjaro, Eli Lilly), have risen in popularity because of their efficacy for glycemic control and weight loss promotion

Our results show that the interactions between P9 and ICAM-2 could be targeted by therapeutics for metabolic diseases

These doses were used within a controlled research environment with rigorous safety monitoring they do not represent guidance for use outside of trials