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BMJ Med 1(1):e000308 Pathak RK, Middeldorp ME, Meredith M, Mehta AB, Mahajan R, Wong CX et al (2015) Long-term effect of goal-directed weight management in an atrial fibrillation cohort: a long-term follow-up study (LEGACY)

Weight loss happens for many reasons: diet changes, exercise, placebo effect, or using other treatments at the same time

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These effects typically resolve within one to two weeks of adjusting to the new dose, following the same adaptation pattern you experienced initially