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Consequently, these models are best suited for investigating acute innate immune responses or tumorimmune interactions, whereas adaptive immune mechanisms are more appropriately studied in immunocompetent adult zebrafish or humanized mouse models

Squares, triangles and circles represent biological repeats

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inhibition of the NF-B inflammatory pathway and protection against oxidative tissue stress

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The definitive diagnosis of adolescent PCOS poses a significant challenge due to the substantial overlap of symptoms with normal physiological characteristics of adolescence