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The clear winner is oral semaglutide, a GLP-1 drug now FDA-approved as a 25 mg pill for weight management since December 2025, with large human trials behind it

Antico O, Thompson PW, Hertz NT et al (2025) Targeting mitophagy in neurodegenerative diseases

None of the Salk teams experiments were conducted in humans, yet the relevance remains

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