This systematic review of the 13 controlled trials in 3,629 patients, involving 250 deaths, 220 cases of new heart failure, and 38 recurrent heart attacks, found that L-carnitine was associated with: Advertisement Significant 27% reduction in all-cause mortality (number needed to treat 38) Highly significant 65% reduction in ventricular arrhythmias (number needed to treat 4) Significant 40% reduction in the development of angina (number needed to treat 3) Reduction in infarct size There were numerically fewer myocardial reinfarctions and heart failure cases associated with L-carnitine, but this did not reach statistical significance.First author James J
Cons: Allergic Reactions: May cause reactions in individuals allergic to ragweed, daisies or marigolds
The financial and opportunity cost must be considered to assess whether it is in the best interests of the research community, considering associated risks of trial failure
Barnosky, A
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According to the requirements of the national food and drug administration 'drug registration management method', the test scheme is designed and the test work is completed, and the results are as follows: (1) in the high-stability injection reduced glutathione vascular irritation test, the rabbit ear marginal vein control group, the market-sold group and the tested group have no hyperemia, hemorrhage and degenerative necrosis phenomena, and have no pathological damage, which indicates that the high-stability injection reduced glutathione (the sample with the batch number of YJ110401 is selected by the invention) does not generate irritation reaction on the rabbit ear vascular by intravenous administration