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VHE is typically characterized by acute onset of impaired consciousness, focal neurologic symptoms and increased seizure frequency [69]

These can range from leaky gut and inflammatory bowel disease to mast cell activation syndrome (MCAS) and anxiety, contributing to neurological dysfunction

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[DOI] [PMC free article] [PubMed] [Google Scholar] 223.Waxman E.A

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Ongoing clinical trials and translational research contribute to the translation of basic scientific knowledge into practical applications for diagnosis, treatment, and prevention