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Across the whole published human programme, 63 healthy adults received CJC-1295 DAC at 30250 mcg/kg, 87% of them men, and 73% of them received a single injection [11]

The phase transition related to higher temperature to physiological temperature are known to induce the release of the drugs

The questions were inspired by questionnaires from other self-medication questionnaires 20 , 21 and patient and public engagement

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Published pharmaceutical literature describes the physiological response to injected endotoxins: fever (pyrogenic response), injection-site inflammation, and systemic inflammatory markers at higher exposure levels

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