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Structurally unique GLP-1-based medicines that achieve substantially greater and rapid weight loss may impact musculoskeletal health, providing a rationale for therapeutics that more selectively target adipose tissue loss while preserving muscle mass and strength

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[40] evaluated the effects of liraglutide on cardiovascular risk biomarkers such as adiponectin, leptin, high-sensitivity C-reactive protein (hs-CRP), interleukin 6 (IL-6), tumor necrosis factor (TNF-), plasminogen activator inhibitor 1 (PAI-1), and B-type natriuretic peptide (BNP)

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