Patients typically notice a looser waistband, reduced bloating, and a flatter appearance around the lower abdomen
*Patients on iron tablets will have black stool, so ensure to clarify the temporal sequence for any symptoms with the starting of iron tablets Investigations Initial Investigations All patients with suspected melena should undergo routine blood tests , including FBC, U&Es, LFTs, and clotting, to help investigate for underlying causes and to stratify overall risk
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According to the Patel 2024 SURPASS trial analysis in Diabetes, Obesity and Metabolism , across 6,263 patients, vomiting occurred in 2% to 13% on tirzepatide depending on dose
Conventional Treatment Topical (eg, corticosteroids and vitamin D analogs): first-line treatment for mild psoriasis Systemic medications: affect the whole body
Strong evidence suggests that GLP-1 agonists have additional beneficial effects beyond glycemic regulation and weight loss, including cardiovascular risk reduction and anti-inflammation
