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Nausea, vomiting, diarrhea, and constipation remain the most common issues

The EECs are the main cells involved in the production and secretion of a variety of hormones and signaling molecules in the GBA

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Alterations in mitochondrial functions such as oxidative phosphorylation (OXPHOS) and membrane polarity, which enhance oxidative stress and apoptosis, may precede the development of depressive symptoms [84, 88, 89]