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oral administration of a single dose of 3 grams of glutathione to health humans does not increase circulating glutathione to a clinically beneficial extent (Witschi et al., The Systemic Availability of Oral Glutathione, Eur

doi: 10.1007/S00394-023-03086-Z 113

In summary, these experiments demonstrated that (i) GSH can replace the natural bound factor, (ii) that Cys-Gly (CG), the initial breakdown product of GSH 9 , also binds at the I site and (iii) that GSH binds more strongly than CG (Fig

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