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Effect of glucagon-like peptide-1 receptor agonists and co-agonists on body composition: Systematic review and network meta-analysis

Retrieved 3 July 2023

adjusted HR, 1.79

The WHO further notes that obesity significantly increases the risk of cardiovascular disease, stroke and type 2 diabetes, while additional research has linked excess weight to chronic kidney disease and rising healthcare expenditures, creating substantial pressure on healthcare systems globally

In a rodent model, a novel GLP-1R/GIPR/GCGR triple agonist, SAR441255, has been shown to promote weight loss and the maintenance of healthy blood glucose levels and is superior to the GLP-1R/GCGR dual agonist (Saxena et al., 2023)

the next section will localize the impact for Houston residents and contrast market realities with the new national pricing options