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Footnotes: 1) Hayashi N, Iida T, Yamada T, Okuma K, Takehara I, Yamamoto T, Yamada K, Tokuda M. Study on the postprandial blood glucose suppression effect of D-psicose in borderline diabetes and the safety of long-term ingestion by normal human subjects. Biosci Biotechnol Biochem. 2010;74(3):510-9. doi: 10.1271/bbb.90707. Epub 2010 Mar 7. PMID: 20208358

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Clin Exp Immunol 147(2):359369 Schorah CJ, Downing C, Piripitsi A, Gallivan L, Al-Hazaa AH, Sanderson MJ, Bodenham A (1996) Total vitamin C, ascorbic acid, and dehydroascorbic acid concentrations in plasma of critically ill patients

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Youll note the boxes that Lilly highlighted in red, the placebo arm, 3mg arm and 3/6/9mg arm all have similar rates of side effects with just slightly higher rates of nausea, fatigue and diarrhea in the 3/6/9mg arm

At low concentrations, ROS show beneficial effects by increasing wound healing, repairing processes, as well as prevent the growth of pathogens or germs by killing them whereas higher amount of ROS causes oxidative stress [5]