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Several smaller biotechnology companies are also attracting attention from larger pharmaceutical players, including Viking Therapeutics and Zealand Pharma, whose programmes are widely viewed as potential licensing or acquisition targets

GLP-1 receptor agonists like semaglutide (the active ingredient in Ozempic) primarily regulate blood sugar and appetite through the gut-brain axis, with secondary effects on blood pressure and cardiovascular function

Decreased and/or low muscle and bone mass negatively impact health, including physical impairment or disability, falls and fractures, surgical complications, reduced quality of life, and decreased survival

Addressing modifiable risk factors remains the cornerstone of prevention and management

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Kinnula VL, Crapo JD