In rats with chronic liver failure, brain edema occurred from the combined effects of hyperammonemia and systemic oxidative stress, with allopurinol, a xanthine oxidase inhibitor, treatment attenuating both oxidative stress and brain edema [62]
Glutathione is the master antioxidant but there are many other antioxidants which are helpful, including vitamin C, vitamin E, quercetin, beta glucans (eg from medicinal mushrooms), zinc, selenium, and others
Zinc inhibition of cellular energy production: implications for mitochondria and neurodegeneration
The delivery system includes those which by-pass gut and liver and thus first pass effect / metabolism
Symptoms of chronic heavy metal toxicity (described later in this protocol) can be similar to other health conditions and may not be immediately recognized as intoxications
Brazil Research suggests that senescent cells impair proteasome activity in the heart, leading to the accumulation of damaged proteins and reduced cardiac function