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Impaired NO synthesis or increased NO degradation due to oxidative stress reduces vasodilatory capacity, promotes vasoconstriction, and enhances vascular tone, contributing to hypertension and ischemia (36, 37)

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Understanding Semaglutide and Its Benefits Semaglutide is an FDA-approved GLP-1 receptor agonist used for managing chronic weight in adults with obesity or who are overweight with at least one weight-related health condition

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In reproductive physiology, melatonin exerts endocrine, autocrine, intracrine, and paracrine effects in the placenta (101)

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