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Glutathione possesses natural antioxidant properties and protects the body against free radicals released as a by-product of metabolic activities

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Assessment of oxidative damage induced by acute doses of morphine sulfate in postnatal and adult rat brain

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7, 8 One of the antioxidant enzymes protecting against oxidative stress is glutathione peroxidase (GPx), which reduces hydrogen peroxide (H 2 O 2 ) and organic hydroperoxides to H 2 O and the corresponding alcohols using reduced glutathione as an essential co-substrate

Activated RIPK3 can induce mtROS production by binding to the E3 subunit of the pyruvate dehydrogenase complex [99]