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BPC-157 is primarily investigated for its effects on angiogenic and NO-mediated signaling
Diabetes causes the BBB leakage via downregulation of tight junction proteins, leading to dysfunctions of endothelial cells, pericytes, astrocytes, microglia, NG2-glia, and oligodendrocytes
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(ii) the static modification of carbamidomethyl on cysteines (+57.021 Da), the dynamic modifications of oxidation on methionine (+15.995 Da) and deamidation on asparagine and glutamine (+0.984 Da)
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