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A systematic review comparing the efficacy outcomes of topical treatments in scalp psoriasis found that topical corticosteroid monotherapy was more effective in clearing scalp psoriatic lesions than vitamin D analog monotherapy [9]

It has shown activity at very low doses (nanogram to microgram per kilogram) without demonstrable toxicity in animal studies [11]

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Fortunately, you cannot overdose on vitamin B12, as it is water-soluble, so adding more is not harmful

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Inhibition of 11beta-hydroxysteroid dehydrogenase type 1 reduces food intake and weight gain but maintains energy expenditure in diet-induced obese mice