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Enzymes cleave the ALCAR molecule, separating it back into free L-carnitine and a free acetyl group

When applied to skin, it's converted through a two-step enzymatic process - first to retinaldehyde, then to retinoic acid - before it becomes biologically active

doi: 10.1016/j.scitotenv.2022.157861 10 ZhangAMatsushitaMZhangLWangHShiXGuHet al

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and E.T

Volunteers may need to take time off from work or make arrangements with their families due to the potential duration of the trial