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In addition, GLP-1RAs promote fullness and satiety [72]

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In addition, in HFD-induced and palmitate (PA)-induced primary mouse cardiomyocyte models, increased expression of bromodomain protein 4 (BRD4) was found to inhibit PINK1/Parkin-mediated mitophagy, leading to impaired cardiac function, and the use of a BRD4 inhibitor (JQ1) was able to activate PINK1/Parkin-mediated mitophagy, thereby playing a therapeutic role in the treatment of DCM [184]