The puzzle was that all these peptides worked through a receptor that had no known natural ligand
PTEN- and p53-mediated apoptosis and cell cycle arrest by FTY720 in gastric cancer cells and nude mice
Cholesterol, in particular, is a member of the lipid family crucial for the growth and function of eukaryotic cells (Mouritsen and Zuckermann, 2004)
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Moreover, Fer-1 and Lip-1 have been evaluated for efficacy against viral infections and neurodegeneration (Wang et al., 2021)