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Urban living environments often concentrate multiple environmental stressors, creating cumulative oxidative burdens that exceed the body's natural antioxidant capacity

Extraction included model/species, sex, dose/route/duration, tissue, controls, redox biomarkers, clinical outcomes, and safety

Redox Signal 11 , 10591081 (2009)

Furthermore, neurons are directly impaired by reactive oxygen and nitrogen species (ROS/NRs) and inflammatory cytokines [270]

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