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Author Contributions Aleksandrina Ruseva, Wojciech Michalak, Anthony Fabricatore, Brain Hartaigh, and Zhenxiang Zhao were responsible for the study concept and design, data interpretation and analysis, drafting/revising the manuscript, and reviewing/approving the final version for submission

doi: 10.1186/s12888-020-02730-w

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Importantly, aging-related cognitive decline is associated with a chronic, low-grade enteric and central inflammatory state, including an increase in microglia, T cells, and border-associated macrophages in the CNS, as well as altered gut microbiota (432, 433)

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Efficient targeting of HIF-1alpha mediated by YC-1 and PX-12 encapsulated niosomes: potential application in colon cancer therapy