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Sources FDA Access Data: MOUNJARO (tirzepatide) injection, for subcutaneous use Full Prescribing Information NCBI StatPearls: Tirzepatide Nature Medicine: Tirzepatide Once Weekly for the Treatment of Obesity Diabetes Therapy: Impact of Morning vs

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A long-acting glucose-dependent insulinotropic polypeptide receptor agonist improves the gastrointestinal tolerability of glucagon-like peptide-1 receptor agonist therapy

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GLP-1 Receptor Activation The GLP-1 component suppresses appetite by signaling the hypothalamus, slows gastric emptying so food stays in the stomach longer, and improves insulin sensitivity