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This review will address the detrimental effect of ceramides on mitochondria membrane composition, respiratory chain, ROS dynamics and mitophagy in brain contributing to neurodegeneration

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Mayatepek E, Okun JG, Meissner T, Assmann B, Hammond J, Zschocke J, Lehmann WD: Synthesis and metabolism of leukotrienes in gamma-glutamyl transpeptidase deficiency

Maintaining sperm quality requires regular moderate-intensity exercise, since it has been demonstrated to boost mitochondrial function, lower systemic inflammation, and strengthen endogenous antioxidant defense mechanisms [53, 54]

These cells showed impaired ferritinophagy and a smaller LIP, which resulted in mitochondrial dysfunction and impaired respiration due to defective synthesis of ISC-proteins such as SDHB

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