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PROVENGE (Sipuleucel-T) in prostate cancer: the first FDA-approved therapeutic cancer vaccine

clinicians independently decide on prescribing, pharmacies fill prescriptions after approval, and the platform limits itself to billing, access management, and coordination rather than medical decision-making

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The current fiscal strategy marks a turning point: from expansion to cost containment

The population studies have also shown a link between CYP2R1, GC (VDBP), CYP24A1, and VDR with that of circulating 25(OH)VD concentrations